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Theacrine

Theacrine

Classification: Zinc Salt

CAS NO.: 2309-49-1

Molecular Formula: C9H12N4O3

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Details

Product Characteristics:

Theacrine (1,3,7,9-tetramethyluric acid) is a purine alkaloid found in the leaves of wild bitter tea (Camellia kucha Hung T. Chang). Its molecular structure contains one more methyl group than caffeine, a common alkaloid in tea leaves. This additional methyl group endows Theacrine with physiological functions and health benefits distinct from those of caffeine, attracting extensive attention from scholars in academia and the medical field. As a methylpurine drug, Theacrine has the following effects: strengthening the heart, promoting diuresis, dilating the coronary arteries, relaxing bronchial smooth muscles, and stimulating the central nervous system. It is mainly used for the treatment of bronchial asthma, emphysema, bronchitis, and cardiac dyspnea.


Technical Data (Executive Standard USP41)

Test Items
Test Standard
Test Method
Character
A  White to almost white crystalline powder
ZSQB12-2
Identification
Passed testHPLC
Theacrine content
≥99.0%HPLC
Loss on dry
<1.0%USP41
Related substance
isolate impurity <0.2%, total impurities<1.0%HPLC
Solubility(water)

ZSQB12-2
Solubility(ethanol)

ZSQB12-2
Residue on ignition
≤0.5%USP41
Ash content
≤0.5%USP41
Melting point
227-232°CUSP41
Heavy Metal
<10ppmUSP41<231>
Pb
≤0.5ppmUSP41<251>
Cd
≤0.5ppmUSP41<231>
As
≤0.5ppmUSP41<211>
Total Plate Count
≤1000cfu/gUSP41<2021>/<2022>
Total Yeast&Mold
≤100cfu/gUSP41<2021>/<2022>
Staphylococcus aureus
NegativeUSP41<2021>/<2022>
P.aeruginosa
NegativeUSP41<61>/<62>
Salmonella
NegativeUSP41<2021>/<2022>
Escherichia ColiNegativeUSP41<2021>/<2022>
Bulk Density
≥0.55g/mlUSP41<616>


Applications:

Theacrine, also known as TeaCrine, is a natural alkaloid derived from plant extracts. Its molecular structure resembles that of caffeine, but it possesses unique stimulating properties, particularly remarkable in enhancing energy, improving mental clarity, and boosting mood. Traditionally, Theacrine is found in bitter tea, which has a long-standing history in Asian cultures. TeaCrine is applied in pre-workout nitrogen pump products, aiming to deliver sustained energy, reduce anxiety, and significantly enhance physical performance.

Theacrine enhances dopamine production by activating dopaminergic receptors D1 and D2. Dopamine is known to boost energy, improve mood, and enhance mental focus. Meanwhile, it inhibits adenosine production – adenosine promotes sedation and relaxation, so blocking it elevates alertness, attention, physical coordination, and exercise performance. Compared to caffeine, Theacrine provides more sustained energy without causing significant crashes or tolerance issues. It is compatible with various pre-workout formulas, including caffeine, creatine, proteins, amino acids, and other pre-workout supplements.

Additionally, Theacrine possesses anti-inflammatory properties, helping to reduce post-workout muscle and joint discomfort. As an antioxidant, it aids in mitigating oxidative stress during exercise, such as lowering inflammation marker levels and minimizing tissue damage after oral intake.

To maximize Theacrine's anti-fatigue and performance-enhancing effects, it is recommended to take it in the morning or 15–30 minutes before exercise. Pure Theacrine powder can be mixed with water or combined with other supplements. The most effective dosage is 25–50 mg per serving. Theacrine begins to take effect 15–30 minutes after ingestion, with users experiencing a steady increase in energy, clear focus, and enhanced attention. Consistent use, combined with a balanced diet and exercise, will lead to comprehensive performance improvement within the first two weeks.


Packaging and Storage:

This product is packaged in kraft paper bags, 25kg per bag, and can also be customized according to user requirements. It should be sealed and stored in a cool, dry place away from light, with a shelf life of twenty-four months.


Safety Protection:

This product should be kept away from contact with eyes, skin, or clothing. In case of splashing onto the body, immediately rinse with plenty of water.


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